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Computational Model of Membrane Fission Catalyzed by ESCRT-III

ESCRT-III proteins catalyze membrane fission during multi vesicular body biogenesis, budding of some enveloped viruses and cell division. We suggest and analyze a novel mechanism of membrane fission by the mammalian ESCRT-III subunits CHMP2 and CHMP3. We propose that the CHMP2-CHMP3 complexes self-a...

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Detalles Bibliográficos
Autores principales: Fabrikant, Gur, Lata, Suman, Riches, James D., Briggs, John A. G., Weissenhorn, Winfried, Kozlov, Michael M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773929/
https://www.ncbi.nlm.nih.gov/pubmed/19936052
http://dx.doi.org/10.1371/journal.pcbi.1000575