Cargando…
Identification of Host Cytosolic Sensors and Bacterial Factors Regulating the Type I Interferon Response to Legionella pneumophila
Legionella pneumophila is a gram-negative bacterial pathogen that replicates in host macrophages and causes a severe pneumonia called Legionnaires' Disease. The innate immune response to L. pneumophila remains poorly understood. Here we focused on identifying host and bacterial factors involved...
Autores principales: | Monroe, Kathryn M., McWhirter, Sarah M., Vance, Russell E. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773930/ https://www.ncbi.nlm.nih.gov/pubmed/19936053 http://dx.doi.org/10.1371/journal.ppat.1000665 |
Ejemplares similares
-
A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP
por: McWhirter, Sarah M., et al.
Publicado: (2009) -
Nutrient generation and retrieval from the host cell cytosol by intra-vacuolar Legionella pneumophila
por: Price, Christopher T. D., et al.
Publicado: (2014) -
Inflammasome-mediated cell death in response to bacterial pathogens that access the host cell cytosol: lessons from legionella pneumophila
por: Casson, Cierra N., et al.
Publicado: (2013) -
Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection
por: Molofsky, Ari B., et al.
Publicado: (2006) -
Secreted Bacterial Effectors That Inhibit Host Protein Synthesis Are Critical for Induction of the Innate Immune Response to Virulent Legionella pneumophila
por: Fontana, Mary F., et al.
Publicado: (2011)