Cytokeratin 8 ectoplasmic domain binds urokinase-type plasminogen activator to breast tumor cells and modulates their adhesion, growth and invasiveness

BACKGROUND: Generation of plasmin is a characteristic of tumor cells, promoting the degradation of extracellular matrix, tumor progression and metastasis. The process is accelerated if plasminogen and plasminogen activator are bound to their cell surface receptors. RESULTS: In this study we show tha...

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Detalles Bibliográficos
Autores principales: Obermajer, Nataša, Doljak, Bojan, Kos, Janko
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774675/
https://www.ncbi.nlm.nih.gov/pubmed/19845941
http://dx.doi.org/10.1186/1476-4598-8-88

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