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The transcription factor ELF4 controls proliferation and homing of CD8(+) T cells via the Krüppel-like factors KLF4 and KLF2
Transcription factors that regulate quiescence, proliferation, and homing of lymphocytes are critical for effective immune system function. In the present study, we demonstrated that the transcription factor ELF4 directly activates the tumor suppressor KLF4 downstream of T cell receptor (TCR) signal...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774797/ https://www.ncbi.nlm.nih.gov/pubmed/19412182 http://dx.doi.org/10.1038/ni.1730 |