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S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo

OBJECTIVE: Vascular smooth muscle cell (VSMC) proliferation plays an important role in the development of postangioplasty or in-stent restenosis, venous graft failure, and atherosclerosis. Our previous work has demonstrated S-phase kinase-associated protein-2 (Skp2), an F-box subunit of SCF(Skp2) ub...

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Detalles Bibliográficos
Autores principales: Wu, Yih-Jer, Sala-Newby, Graciela B., Shu, Kuo-Tung, Yeh, Hung-I., Nakayama, Keiichi I., Nakayama, Keiko, Newby, Andrew C., Bond, Mark
Formato: Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774860/
https://www.ncbi.nlm.nih.gov/pubmed/19878790
http://dx.doi.org/10.1016/j.jvs.2009.07.066