Cargando…

S-phase kinase-associated protein-2 (Skp2) promotes vascular smooth muscle cell proliferation and neointima formation in vivo

OBJECTIVE: Vascular smooth muscle cell (VSMC) proliferation plays an important role in the development of postangioplasty or in-stent restenosis, venous graft failure, and atherosclerosis. Our previous work has demonstrated S-phase kinase-associated protein-2 (Skp2), an F-box subunit of SCF(Skp2) ub...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Yih-Jer, Sala-Newby, Graciela B., Shu, Kuo-Tung, Yeh, Hung-I., Nakayama, Keiichi I., Nakayama, Keiko, Newby, Andrew C., Bond, Mark
Formato:	Texto
Lenguaje:	English
Publicado:	Elsevier 2009
Materias:	Basic Research Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774860/ https://www.ncbi.nlm.nih.gov/pubmed/19878790 http://dx.doi.org/10.1016/j.jvs.2009.07.066

Ejemplares similares

PKA and Epac synergistically inhibit smooth muscle cell proliferation
por: Hewer, Richard C., et al.
Publicado: (2011)

USP10 exacerbates neointima formation by stabilizing Skp2 protein in vascular smooth muscle cells
por: Xia, Xiaohong, et al.
Publicado: (2021)

Impaired germ cell development due to compromised cell cycle progression in Skp2-deficient mice
por: Fotovati, Abbas, et al.
Publicado: (2006)

The Hippo pathway mediates inhibition of vascular smooth muscle cell proliferation by cAMP
por: Kimura, Tomomi E., et al.
Publicado: (2016)

Defective autophagy in vascular smooth muscle cells accelerates senescence and promotes neointima formation and atherogenesis
por: Grootaert, Mandy OJ, et al.
Publicado: (2015)

Zoledronate upregulates MMP-9 and -13 in rat vascular smooth muscle cells by inducing oxidative stress
por: Arun, Mehmet Zuhuri, et al.
Publicado: (2016)

The Amelioration of Renal Damage in Skp2-Deficient Mice Canceled by p27 (Kip1) Deficiency in Skp2(−/−) p27(−/−) Mice
por: Suzuki, Sayuri, et al.
Publicado: (2012)

Targeting Wnt/β-Catenin Activated Cells with Dominant-Negative N-cadherin to Reduce Neointima Formation
por: Hulin-Curtis, Sarah, et al.
Publicado: (2017)

p107 inhibits G1 to S phase progression by down-regulating expression of the F-box protein Skp2
por: Rodier, Geneviève, et al.
Publicado: (2005)

Divergent Regulation of Actin Dynamics and Megakaryoblastic Leukemia-1 and -2 (Mkl1/2) by cAMP in Endothelial and Smooth Muscle Cells
por: Smith, Madeleine C., et al.
Publicado: (2017)

cAMP-induced actin cytoskeleton remodelling inhibits MKL1-dependent expression of the chemotactic and pro-proliferative factor, CCN1
por: Duggirala, Aparna, et al.
Publicado: (2015)

Skp2 suppresses apoptosis in Rb1 deficient tumors by limiting E2F1 activity
por: Lu, Zhonglei, et al.
Publicado: (2014)

Protein kinase CK2 inhibition suppresses neointima formation via a proline-rich homeodomain-dependent mechanism
por: Wadey, K.S., et al.
Publicado: (2017)

Ending Restenosis: Inhibition of Vascular Smooth Muscle Cell Proliferation by cAMP
por: Smith, Sarah A., et al.
Publicado: (2019)

Bilirubin Inhibits Neointima Formation and Vascular Smooth Muscle Cell Proliferation and Migration
por: Peyton, Kelly J., et al.
Publicado: (2012)

EC4, a truncation of soluble N-cadherin, reduces vascular smooth muscle cell apoptosis and markers of atherosclerotic plaque instability
por: Lyon, Cressida A, et al.
Publicado: (2014)

Previously differentiated medial vascular smooth muscle cells contribute to neointima formation following vascular injury
por: Herring, Brian Paul, et al.
Publicado: (2014)

Role of FOXM1 in vascular smooth muscle cell survival and neointima formation following vascular injury
por: Franco, Sarah, et al.
Publicado: (2020)

SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination
por: Lu, Wenfu, et al.
Publicado: (2014)

Inhibiting Skp2 E3 Ligase Suppresses Bleomycin-Induced Pulmonary Fibrosis
por: Mikamo, Masashi, et al.
Publicado: (2018)

Oxidative stress induces early-onset apoptosis of vascular smooth muscle cells and neointima formation in response to injury
por: Gomez, Camilo, et al.
Publicado: (2015)

Inhibition of STAT3 signaling prevents vascular smooth muscle cell proliferation and neointima formation
por: Daniel, Jan-Marcus, et al.
Publicado: (2012)

Gastrodin inhibits cell proliferation in vascular smooth muscle cells and attenuates neointima formation in vivo
por: ZHU, LIHUA, et al.
Publicado: (2012)

Genistein suppresses leptin‐induced proliferation and migration of vascular smooth muscle cells and neointima formation
por: Tsai, Yung‐Chieh, et al.
Publicado: (2016)

Poldip2 Knockdown Inhibits Vascular Smooth Muscle Proliferation and Neointima Formation by Regulating the Expression of PCNA and p21
por: Datla, Srinivasa Raju, et al.
Publicado: (2018)

Interferon Regulatory Factor 7 Protects Against Vascular Smooth Muscle Cell Proliferation and Neointima Formation
por: Huang, Ling, et al.
Publicado: (2014)

Xanthohumol Blocks Proliferation and Migration of Vascular Smooth Muscle Cells in Vitro and Reduces Neointima Formation in Vivo
por: Liu, Rongxia, et al.
Publicado: (2017)

Regulation of Epigenetic Modifiers, Including KDM6B, by Interferon-γ and Interleukin-4 in Human Macrophages
por: Yıldırım-Buharalıoğlu, Gökçe, et al.
Publicado: (2017)

Parent artery-initiated and stent-mediated neointima formation in a rat saccular side wall model
por: Wanderer, Stefan, et al.
Publicado: (2022)

NF2 deficiency accelerates neointima hyperplasia following vascular injury via promoting YAP-TEAD1 interaction in vascular smooth muscle cells
por: Sun, Xiongshan, et al.
Publicado: (2020)

Dual Role of CREB in The Regulation of VSMC Proliferation: Mode of Activation Determines Pro- or Anti-Mitogenic Function
por: Hudson, Claire, et al.
Publicado: (2018)

MT1-matrix metalloproteinase directs arterial wall invasion and neointima formation by vascular smooth muscle cells
por: Filippov, Sergey, et al.
Publicado: (2005)

PDZK1 Prevents Neointima Formation via Suppression of Breakpoint Cluster Region Kinase in Vascular Smooth Muscle
por: Lee, Wan Ru, et al.
Publicado: (2015)

miR-22 Is a Novel Mediator of Vascular Smooth Muscle Cell Phenotypic Modulation and Neointima Formation
por: Yang, Feng, et al.
Publicado: (2018)

Tollip Negatively Regulates Vascular Smooth Muscle Cell–Mediated Neointima Formation by Suppressing Akt‐Dependent Signaling
por: Zhi, Hong, et al.
Publicado: (2018)

Homer binds to Orai1 and TRPC channels in the neointima and regulates vascular smooth muscle cell migration and proliferation
por: Jia, Shuping, et al.
Publicado: (2017)

TSPO ligands prevent the proliferation of vascular smooth muscle cells and attenuate neointima formation through AMPK activation
por: Wu, Lian-pan, et al.
Publicado: (2019)

Smooth muscle cells-specific loss of OCT4 accelerates neointima formation after acute vascular injury
por: Shin, Junchul, et al.
Publicado: (2023)

Smooth Muscle–Selective Inhibition of Nuclear Factor‐κB Attenuates Smooth Muscle Phenotypic Switching and Neointima Formation Following Vascular Injury
por: Yoshida, Tadashi, et al.
Publicado: (2013)

BRD4770 inhibits vascular smooth muscle cell proliferation via SUV39H2, but not EHMT2 to protect against neointima formation
por: Chen, Tai-Qiang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_89cmmnm2st49fblahr0jkl24e8