Transcriptional Regulation and Biological Functions of Selenium-Binding Protein 1 in Colorectal Cancer In Vitro and in Nude Mouse Xenografts

BACKGROUND: It has been shown that selenium-binding protein 1 (SBP1) is significantly downregulated in different human cancers. Its regulation and function have not yet been established. METHODOLOGY AND PRINCIPAL FINDINGS: We show that the SBP1 promoter is hypermethylated in colon cancer tissues and...

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Detalles Bibliográficos
Autores principales: Pohl, Nicole M., Tong, Chang, Fang, Wenfeng, Bi, Xiuli, Li, Tianhong, Yang, Wancai
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774949/
https://www.ncbi.nlm.nih.gov/pubmed/19924303
http://dx.doi.org/10.1371/journal.pone.0007774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774949/
https://www.ncbi.nlm.nih.gov/pubmed/19924303
http://dx.doi.org/10.1371/journal.pone.0007774

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