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Experimental Diabetes Mellitus Exacerbates Tau Pathology in a Transgenic Mouse Model of Alzheimer's Disease

Diabetes mellitus (DM) is characterized by hyperglycemia caused by a lack of insulin, insulin resistance, or both. There is increasing evidence that insulin also plays a role in Alzheimer's disease (AD) as it is involved in the metabolism of β-amyloid (Aβ) and tau, two proteins that form Aβ pla...

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Detalles Bibliográficos
Autores principales:	Ke, Yazi D., Delerue, Fabien, Gladbach, Amadeus, Götz, Jürgen, Ittner, Lars M.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775636/ https://www.ncbi.nlm.nih.gov/pubmed/19936237 http://dx.doi.org/10.1371/journal.pone.0007917

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