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Key Role of the GITR/GITRLigand Pathway in the Development of Murine Autoimmune Diabetes: A Potential Therapeutic Target
BACKGROUND: The cross-talk between pathogenic T lymphocytes and regulatory T cells (Tregs) plays a major role in the progression of autoimmune diseases. Our objective is to identify molecules and/or pathways involved in this interaction and representing potential targets for innovative therapies. Gl...
Autores principales: | You, Sylvaine, Poulton, Lynn, Cobbold, Steve, Liu, Chih-Pin, Rosenzweig, Michael, Ringler, Douglas, Lee, Wen-Hui, Segovia, Berta, Bach, Jean-François, Waldmann, Herman, Chatenoud, Lucienne |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775640/ https://www.ncbi.nlm.nih.gov/pubmed/19936238 http://dx.doi.org/10.1371/journal.pone.0007848 |
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