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Gender Difference in the Prodromal Symptoms of First-episode Schizophrenia
To investigate the gender difference of early symptoms appearing before the onset of the psychotic symptoms in patients with first-episode schizophrenia, we reviewed the medical records of 63 patients (38 males, 25 females), who were hospitalized for first-episode schizophrenia. The frequency and du...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
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The Korean Academy of Medical Sciences
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775856/ https://www.ncbi.nlm.nih.gov/pubmed/19949664 http://dx.doi.org/10.3346/jkms.2009.24.6.1083 |
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author | Choi, Jung-Seok Chon, Myong-Wuk Kang, Do-Hyung Jung, Myung Hun Kwon, Jun Soo |
author_facet | Choi, Jung-Seok Chon, Myong-Wuk Kang, Do-Hyung Jung, Myung Hun Kwon, Jun Soo |
author_sort | Choi, Jung-Seok |
collection | PubMed |
description | To investigate the gender difference of early symptoms appearing before the onset of the psychotic symptoms in patients with first-episode schizophrenia, we reviewed the medical records of 63 patients (38 males, 25 females), who were hospitalized for first-episode schizophrenia. The frequency and duration of prodromal and psychotic symptoms, Clinical Global Impression scale scores, Global Assessment of Functioning (GAF) scale scores at admission, and other clinical characteristics were recorded for all patients. Overall, the most common prodromal symptoms were attenuated positive symptoms (89%), followed by mood symptoms (86%). Negative symptoms were the most common in male patients (97.4%), whereas attenuated positive symptoms were the most common in female patients (84%). Male patients demonstrated more frequent negative, cognitive, and obsessive-compulsive symptoms than female patients did and also showed a tendency of having negative symptoms for the longer period. Correlational analysis showed a significant negative correlation between the duration of negative symptoms and GAF scores at admission in male patients. Our findings suggest that different patterns of prodromal symptoms between male and female begin before the onset of the psychosis. Further prospective studies should be needed. |
format | Text |
id | pubmed-2775856 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | The Korean Academy of Medical Sciences |
record_format | MEDLINE/PubMed |
spelling | pubmed-27758562009-12-01 Gender Difference in the Prodromal Symptoms of First-episode Schizophrenia Choi, Jung-Seok Chon, Myong-Wuk Kang, Do-Hyung Jung, Myung Hun Kwon, Jun Soo J Korean Med Sci Original Article To investigate the gender difference of early symptoms appearing before the onset of the psychotic symptoms in patients with first-episode schizophrenia, we reviewed the medical records of 63 patients (38 males, 25 females), who were hospitalized for first-episode schizophrenia. The frequency and duration of prodromal and psychotic symptoms, Clinical Global Impression scale scores, Global Assessment of Functioning (GAF) scale scores at admission, and other clinical characteristics were recorded for all patients. Overall, the most common prodromal symptoms were attenuated positive symptoms (89%), followed by mood symptoms (86%). Negative symptoms were the most common in male patients (97.4%), whereas attenuated positive symptoms were the most common in female patients (84%). Male patients demonstrated more frequent negative, cognitive, and obsessive-compulsive symptoms than female patients did and also showed a tendency of having negative symptoms for the longer period. Correlational analysis showed a significant negative correlation between the duration of negative symptoms and GAF scores at admission in male patients. Our findings suggest that different patterns of prodromal symptoms between male and female begin before the onset of the psychosis. Further prospective studies should be needed. The Korean Academy of Medical Sciences 2009-12 2009-11-09 /pmc/articles/PMC2775856/ /pubmed/19949664 http://dx.doi.org/10.3346/jkms.2009.24.6.1083 Text en Copyright © 2009 The Korean Academy of Medical Sciences http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Choi, Jung-Seok Chon, Myong-Wuk Kang, Do-Hyung Jung, Myung Hun Kwon, Jun Soo Gender Difference in the Prodromal Symptoms of First-episode Schizophrenia |
title | Gender Difference in the Prodromal Symptoms of First-episode Schizophrenia |
title_full | Gender Difference in the Prodromal Symptoms of First-episode Schizophrenia |
title_fullStr | Gender Difference in the Prodromal Symptoms of First-episode Schizophrenia |
title_full_unstemmed | Gender Difference in the Prodromal Symptoms of First-episode Schizophrenia |
title_short | Gender Difference in the Prodromal Symptoms of First-episode Schizophrenia |
title_sort | gender difference in the prodromal symptoms of first-episode schizophrenia |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775856/ https://www.ncbi.nlm.nih.gov/pubmed/19949664 http://dx.doi.org/10.3346/jkms.2009.24.6.1083 |
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