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Lrp4, a Novel Receptor for Dickkopf 1 and Sclerostin, Is Expressed by Osteoblasts and Regulates Bone Growth and Turnover In Vivo

Lrp4 is a multifunctional member of the low density lipoprotein-receptor gene family and a modulator of extracellular cell signaling pathways in development. For example, Lrp4 binds Wise, a secreted Wnt modulator and BMP antagonist. Lrp4 shares structural elements within the extracellular ligand bin...

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Detalles Bibliográficos
Autores principales: Choi, Hong Y., Dieckmann, Marco, Herz, Joachim, Niemeier, Andreas
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775917/
https://www.ncbi.nlm.nih.gov/pubmed/19936252
http://dx.doi.org/10.1371/journal.pone.0007930