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Anthrax Lethal Toxin Induced Lysosomal Membrane Permeabilization and Cytosolic Cathepsin Release Is Nlrp1b/Nalp1b-Dependent

NOD-like receptors (NLRs) are a group of cytoplasmic molecules that recognize microbial invasion or ‘danger signals’. Activation of NLRs can induce rapid caspase-1 dependent cell death termed pyroptosis, or a caspase-1 independent cell death termed pyronecrosis. Bacillus anthracis lethal toxin (LT),...

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Detalles Bibliográficos
Autores principales:	Averette, Kathleen M., Pratt, Matthew R., Yang, Yanan, Bassilian, Sara, Whitelegge, Julian P., Loo, Joseph A., Muir, Tom W., Bradley, Kenneth A.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2775945/ https://www.ncbi.nlm.nih.gov/pubmed/19924255 http://dx.doi.org/10.1371/journal.pone.0007913

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