Proliferation and survival molecules implicated in the inhibition of BRAF pathway in thyroid cancer cells harbouring different genetic mutations

BACKGROUND: Thyroid carcinomas show a high prevalence of mutations in the oncogene BRAF which are inversely associated with RAS or RET/PTC oncogenic activation. The possibility of using inhibitors on the BRAF pathway as became an interesting therapeutic approach. In thyroid cancer cells the target m...

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Detalles Bibliográficos
Autores principales: Preto, Ana, Gonçalves, Joana, Rebocho, Ana P, Figueiredo, Joana, Meireles, Ana M, Rocha, Ana S, Vasconcelos, Helena M, Seca, Hugo, Seruca, Raquel, Soares, Paula, Sobrinho-Simões, Manuel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776025/
https://www.ncbi.nlm.nih.gov/pubmed/19878585
http://dx.doi.org/10.1186/1471-2407-9-387

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