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Cohesin Is Required for Higher-Order Chromatin Conformation at the Imprinted IGF2-H19 Locus
Cohesin is a chromatin-associated protein complex that mediates sister chromatid cohesion by connecting replicated DNA molecules. Cohesin also has important roles in gene regulation, but the mechanistic basis of this function is poorly understood. In mammalian genomes, cohesin co-localizes with CCCT...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776306/ https://www.ncbi.nlm.nih.gov/pubmed/19956766 http://dx.doi.org/10.1371/journal.pgen.1000739 |