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Role of Toll-Like Receptors 2 and 4 in Pulmonary Inflammation and Injury Induced by Pneumolysin in Mice

BACKGROUND: Pneumolysin (PLN) is an intracellular toxin of Streptococcus pneumoniae that has been implicated as a major virulence factor in infections caused by this pathogen. Conserved bacterial motifs are recognized by the immune system by pattern recognition receptors among which the family of To...

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Detalles Bibliográficos
Autores principales:	Dessing, Mark C., Hirst, Robert A., de Vos, Alex F., van der Poll, Tom
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776357/ https://www.ncbi.nlm.nih.gov/pubmed/19956717 http://dx.doi.org/10.1371/journal.pone.0007993

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