Evolution of virulence in malaria

The pathogenesis of severe malarial disease is not yet fully understood. It is clear that host immunopathology plays a central role, and a recent paper in BMC Evolutionary Biology suggests that the ability of the parasite to stimulate interleukin-10 production is a major factor and speculates on its...

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Detalles Bibliográficos
Autores principales: Penman, Bridget, Gupta, Sunetra
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776394/
https://www.ncbi.nlm.nih.gov/pubmed/18771591
http://dx.doi.org/10.1186/jbiol83
Descripción
Sumario:The pathogenesis of severe malarial disease is not yet fully understood. It is clear that host immunopathology plays a central role, and a recent paper in BMC Evolutionary Biology suggests that the ability of the parasite to stimulate interleukin-10 production is a major factor and speculates on its impact on the coevolution of host and parasite.

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