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A bridge to transcription by RNA polymerase
A comprehensive survey of single amino-acid substitution mutations critical for RNA polymerase function published in Journal of Biology supports a proposed mechanism for polymerase action in which movement of the polymerase 'bridge helix' promotes transcriptional activity in cooperation wi...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776398/ https://www.ncbi.nlm.nih.gov/pubmed/19090964 http://dx.doi.org/10.1186/jbiol99 |
| _version_ | 1782174094647623680 |
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| author | Kaplan, Craig D Kornberg, Roger D |
| author_facet | Kaplan, Craig D Kornberg, Roger D |
| author_sort | Kaplan, Craig D |
| collection | PubMed |
| description | A comprehensive survey of single amino-acid substitution mutations critical for RNA polymerase function published in Journal of Biology supports a proposed mechanism for polymerase action in which movement of the polymerase 'bridge helix' promotes transcriptional activity in cooperation with a critical substrate-interaction domain, the 'trigger loop'. |
| format | Text |
| id | pubmed-2776398 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2008 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-27763982009-11-13 A bridge to transcription by RNA polymerase Kaplan, Craig D Kornberg, Roger D J Biol Minireview A comprehensive survey of single amino-acid substitution mutations critical for RNA polymerase function published in Journal of Biology supports a proposed mechanism for polymerase action in which movement of the polymerase 'bridge helix' promotes transcriptional activity in cooperation with a critical substrate-interaction domain, the 'trigger loop'. BioMed Central 2008 2008-12-02 /pmc/articles/PMC2776398/ /pubmed/19090964 http://dx.doi.org/10.1186/jbiol99 Text en Copyright © 2008 BioMed Central Ltd |
| spellingShingle | Minireview Kaplan, Craig D Kornberg, Roger D A bridge to transcription by RNA polymerase |
| title | A bridge to transcription by RNA polymerase |
| title_full | A bridge to transcription by RNA polymerase |
| title_fullStr | A bridge to transcription by RNA polymerase |
| title_full_unstemmed | A bridge to transcription by RNA polymerase |
| title_short | A bridge to transcription by RNA polymerase |
| title_sort | bridge to transcription by rna polymerase |
| topic | Minireview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776398/ https://www.ncbi.nlm.nih.gov/pubmed/19090964 http://dx.doi.org/10.1186/jbiol99 |
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