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X-chromosome inactivation: the molecular basis of silencing
X-chromosome inactivation occurs randomly for one of the two X chromosomes in female cells during development. Inactivation occurs when RNA transcribed from the Xist gene on the X chromosome from which it is expressed spreads to coat the whole X chromosome. In the first issue of Epigenetics and Chro...
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Formato: | Texto |
Lenguaje: | English |
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BioMed Central
2008
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776401/ https://www.ncbi.nlm.nih.gov/pubmed/18983701 http://dx.doi.org/10.1186/jbiol95 |
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author | Panning, Barbara |
author_facet | Panning, Barbara |
author_sort | Panning, Barbara |
collection | PubMed |
description | X-chromosome inactivation occurs randomly for one of the two X chromosomes in female cells during development. Inactivation occurs when RNA transcribed from the Xist gene on the X chromosome from which it is expressed spreads to coat the whole X chromosome. In the first issue of Epigenetics and Chromatin, Nesterova and colleagues investigate the role of the RNA interference pathway enzyme Dicer in DNA methylation of the Xist promoter. |
format | Text |
id | pubmed-2776401 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2008 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-27764012009-11-13 X-chromosome inactivation: the molecular basis of silencing Panning, Barbara J Biol Minireview X-chromosome inactivation occurs randomly for one of the two X chromosomes in female cells during development. Inactivation occurs when RNA transcribed from the Xist gene on the X chromosome from which it is expressed spreads to coat the whole X chromosome. In the first issue of Epigenetics and Chromatin, Nesterova and colleagues investigate the role of the RNA interference pathway enzyme Dicer in DNA methylation of the Xist promoter. BioMed Central 2008 2008-10-27 /pmc/articles/PMC2776401/ /pubmed/18983701 http://dx.doi.org/10.1186/jbiol95 Text en Copyright © 2008 BioMed Central Ltd |
spellingShingle | Minireview Panning, Barbara X-chromosome inactivation: the molecular basis of silencing |
title | X-chromosome inactivation: the molecular basis of silencing |
title_full | X-chromosome inactivation: the molecular basis of silencing |
title_fullStr | X-chromosome inactivation: the molecular basis of silencing |
title_full_unstemmed | X-chromosome inactivation: the molecular basis of silencing |
title_short | X-chromosome inactivation: the molecular basis of silencing |
title_sort | x-chromosome inactivation: the molecular basis of silencing |
topic | Minireview |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776401/ https://www.ncbi.nlm.nih.gov/pubmed/18983701 http://dx.doi.org/10.1186/jbiol95 |
work_keys_str_mv | AT panningbarbara xchromosomeinactivationthemolecularbasisofsilencing |