Appetite for reproduction: dietary restriction, aging and the mammalian gonad

The major physiologic theory of aging, the disposable soma theory, links dietary restriction (DR), also known as calorie or food restriction, to prolonged lifespan and makes specific predictions about the effects of aging and DR on reproduction. A recent study in BMC Biology profiling the effects of...

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Detalles Bibliográficos
Autores principales: Nalam, Roopa L, Pletcher, Scott D, Matzuk, Martin M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776403/
https://www.ncbi.nlm.nih.gov/pubmed/18828876
http://dx.doi.org/10.1186/jbiol84
Descripción
Sumario:The major physiologic theory of aging, the disposable soma theory, links dietary restriction (DR), also known as calorie or food restriction, to prolonged lifespan and makes specific predictions about the effects of aging and DR on reproduction. A recent study in BMC Biology profiling the effects of aging and DR on gonadal gene expression provides novel molecular evidence that has a significant impact on this theory of aging.

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