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The mannosylated extracellular domain of Her2/neu produced in P. pastoris induces protective antitumor immunity

BACKGROUND: Her2/neu is overexpressed in various human cancers of epithelial origin and is associated with increased metastatic potential and poor prognosis. Several attempts have been made using the extracellular domain of Her2/neu (ECD/Her2) as a prophylactic vaccine in mice with no success in tum...

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Detalles Bibliográficos
Autores principales:	Dimitriadis, Alexios, Gontinou, Chrysanthi, Baxevanis, Constantin N, Mamalaki, Avgi
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776603/ https://www.ncbi.nlm.nih.gov/pubmed/19878568 http://dx.doi.org/10.1186/1471-2407-9-386

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