Targeting TNF-α for cancer therapy

As the tumor vasculature is a key element of the tumor stroma, angiogenesis is the target of many cancer therapies. Recent work published in BMC Cell Biology describes a fusion protein that combines a peptide previously shown to home in on the gastric cancer vasculature with the anti-tumor cytokine...

Descripción completa

Detalles Bibliográficos
Autores principales: Burton, Elizabeth R, Libutti, Steven K
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776910/
https://www.ncbi.nlm.nih.gov/pubmed/19863762
http://dx.doi.org/10.1186/jbiol189
_version_ 1782174118414647296
author Burton, Elizabeth R
Libutti, Steven K
author_facet Burton, Elizabeth R
Libutti, Steven K
author_sort Burton, Elizabeth R
collection PubMed
description As the tumor vasculature is a key element of the tumor stroma, angiogenesis is the target of many cancer therapies. Recent work published in BMC Cell Biology describes a fusion protein that combines a peptide previously shown to home in on the gastric cancer vasculature with the anti-tumor cytokine TNF-α, and assesses its potential for gastric cancer therapy.
format Text
id pubmed-2776910
institution National Center for Biotechnology Information
language English
publishDate 2009
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-27769102010-04-23 Targeting TNF-α for cancer therapy Burton, Elizabeth R Libutti, Steven K J Biol Minireview As the tumor vasculature is a key element of the tumor stroma, angiogenesis is the target of many cancer therapies. Recent work published in BMC Cell Biology describes a fusion protein that combines a peptide previously shown to home in on the gastric cancer vasculature with the anti-tumor cytokine TNF-α, and assesses its potential for gastric cancer therapy. BioMed Central 2009 2009-10-23 /pmc/articles/PMC2776910/ /pubmed/19863762 http://dx.doi.org/10.1186/jbiol189 Text en Copyright © 2009 BioMed Central Ltd
spellingShingle Minireview
Burton, Elizabeth R
Libutti, Steven K
Targeting TNF-α for cancer therapy
title Targeting TNF-α for cancer therapy
title_full Targeting TNF-α for cancer therapy
title_fullStr Targeting TNF-α for cancer therapy
title_full_unstemmed Targeting TNF-α for cancer therapy
title_short Targeting TNF-α for cancer therapy
title_sort targeting tnf-α for cancer therapy
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776910/
https://www.ncbi.nlm.nih.gov/pubmed/19863762
http://dx.doi.org/10.1186/jbiol189
work_keys_str_mv AT burtonelizabethr targetingtnfaforcancertherapy
AT libuttistevenk targetingtnfaforcancertherapy

Ejemplares similares