Insulators as mediators of intra- and inter-chromosomal interactions: a common evolutionary theme

Insulator elements mediate intra- and inter-chromosomal interactions. The insulator protein CCCTC-binding factor (CTCF) is important for insulator function in several animals but a report in BMC Molecular Biology shows that Caenorhabditis elegans, yeast and plants lack CTCF. Alternative proteins may...

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Detalles Bibliográficos
Autores principales: Ong, Chin-Tong, Corces, Victor G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776911/
https://www.ncbi.nlm.nih.gov/pubmed/19725934
http://dx.doi.org/10.1186/jbiol165
Descripción
Sumario:Insulator elements mediate intra- and inter-chromosomal interactions. The insulator protein CCCTC-binding factor (CTCF) is important for insulator function in several animals but a report in BMC Molecular Biology shows that Caenorhabditis elegans, yeast and plants lack CTCF. Alternative proteins may have a similar function in these organisms.

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