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Complementary pathways in mammalian female sex determination
In mammals, the sex of the embryo is determined by the fate of the gonad. Recent papers, including one in BMC Developmental Biology, shed light on the molecular regulation of ovarian development and suggest that the R-spondin1/Wnt4/β-catenin pathway and the Foxl2 transcription factor act in a comple...
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| Formato: | Texto |
| Lenguaje: | English |
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BioMed Central
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776915/ https://www.ncbi.nlm.nih.gov/pubmed/19735582 http://dx.doi.org/10.1186/jbiol173 |
| _version_ | 1782174119606878208 |
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| author | Nef, Serge Vassalli, Jean-Dominique |
| author_facet | Nef, Serge Vassalli, Jean-Dominique |
| author_sort | Nef, Serge |
| collection | PubMed |
| description | In mammals, the sex of the embryo is determined by the fate of the gonad. Recent papers, including one in BMC Developmental Biology, shed light on the molecular regulation of ovarian development and suggest that the R-spondin1/Wnt4/β-catenin pathway and the Foxl2 transcription factor act in a complementary manner to promote ovarian fate and to repress testicular development. |
| format | Text |
| id | pubmed-2776915 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2009 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-27769152010-03-02 Complementary pathways in mammalian female sex determination Nef, Serge Vassalli, Jean-Dominique J Biol Minireview In mammals, the sex of the embryo is determined by the fate of the gonad. Recent papers, including one in BMC Developmental Biology, shed light on the molecular regulation of ovarian development and suggest that the R-spondin1/Wnt4/β-catenin pathway and the Foxl2 transcription factor act in a complementary manner to promote ovarian fate and to repress testicular development. BioMed Central 2009 2009-09-02 /pmc/articles/PMC2776915/ /pubmed/19735582 http://dx.doi.org/10.1186/jbiol173 Text en Copyright © 2009 BioMed Central Ltd |
| spellingShingle | Minireview Nef, Serge Vassalli, Jean-Dominique Complementary pathways in mammalian female sex determination |
| title | Complementary pathways in mammalian female sex determination |
| title_full | Complementary pathways in mammalian female sex determination |
| title_fullStr | Complementary pathways in mammalian female sex determination |
| title_full_unstemmed | Complementary pathways in mammalian female sex determination |
| title_short | Complementary pathways in mammalian female sex determination |
| title_sort | complementary pathways in mammalian female sex determination |
| topic | Minireview |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776915/ https://www.ncbi.nlm.nih.gov/pubmed/19735582 http://dx.doi.org/10.1186/jbiol173 |
| work_keys_str_mv | AT nefserge complementarypathwaysinmammalianfemalesexdetermination AT vassallijeandominique complementarypathwaysinmammalianfemalesexdetermination |