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PKA Mediates Constitutive Activation of CFTR in Human Sweat Duct

The cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) channels are constitutively activated in sweat ducts. Since phosphorylation-dependent and -independent mechanisms can activate CFTR, we sought to determine the actual mechanism responsible for constitutive activation of these chann...

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Detalles Bibliográficos
Autores principales: Reddy, M. M., Quinton, P. M.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776937/
https://www.ncbi.nlm.nih.gov/pubmed/19865788
http://dx.doi.org/10.1007/s00232-009-9205-1