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PKA Mediates Constitutive Activation of CFTR in Human Sweat Duct
The cystic fibrosis transmembrane conductance regulator (CFTR) Cl(−) channels are constitutively activated in sweat ducts. Since phosphorylation-dependent and -independent mechanisms can activate CFTR, we sought to determine the actual mechanism responsible for constitutive activation of these chann...
Autores principales: | Reddy, M. M., Quinton, P. M. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776937/ https://www.ncbi.nlm.nih.gov/pubmed/19865788 http://dx.doi.org/10.1007/s00232-009-9205-1 |
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