Frequent Long-Range Epigenetic Silencing of Protocadherin Gene Clusters on Chromosome 5q31 in Wilms' Tumor

Wilms' tumour (WT) is a pediatric tumor of the kidney that arises via failure of the fetal developmental program. The absence of identifiable mutations in the majority of WTs suggests the frequent involvement of epigenetic aberrations in WT. We therefore conducted a genome-wide analysis of prom...

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Detalles Bibliográficos
Autores principales: Dallosso, Anthony R., Hancock, Anne L., Szemes, Marianna, Moorwood, Kim, Chilukamarri, Laxmi, Tsai, Hsin-Hao, Sarkar, Abby, Barasch, Jonathan, Vuononvirta, Raisa, Jones, Chris, Pritchard-Jones, Kathy, Royer-Pokora, Brigitte, Lee, Sean Bong, Owen, Ceris, Malik, Sally, Feng, Yi, Frank, Marcus, Ward, Andrew, Brown, Keith W., Malik, Karim
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776977/
https://www.ncbi.nlm.nih.gov/pubmed/19956686
http://dx.doi.org/10.1371/journal.pgen.1000745

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