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Insulin Signaling Regulates Mitochondrial Function in Pancreatic β-Cells

Insulin/IGF-I signaling regulates the metabolism of most mammalian tissues including pancreatic islets. To dissect the mechanisms linking insulin signaling with mitochondrial function, we first identified a mitochondria-tethering complex in β-cells that included glucokinase (GK), and the pro-apoptot...

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Detalles Bibliográficos
Autores principales:	Liu, Siming, Okada, Terumasa, Assmann, Anke, Soto, Jamie, Liew, Chong Wee, Bugger, Heiko, Shirihai, Orian S., Abel, E. Dale, Kulkarni, Rohit N.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2776992/ https://www.ncbi.nlm.nih.gov/pubmed/19956695 http://dx.doi.org/10.1371/journal.pone.0007983

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