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Administration of S-nitrosoglutathione after traumatic brain injury protects the neurovascular unit and reduces secondary injury in a rat model of controlled cortical impact
BACKGROUND: Traumatic brain injury (TBI) is a major cause of preventable death and serious morbidity in young adults. This complex pathological condition is characterized by significant blood brain barrier (BBB) leakage that stems from cerebral ischemia, inflammation, and redox imbalances in the tra...
Autores principales: | Khan, Mushfiquddin, Im, Yeong-Bin, Shunmugavel, Anandakumar, Gilg, Anne G, Dhindsa, Ramanpreet K, Singh, Avtar K, Singh, Inderjit |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777134/ https://www.ncbi.nlm.nih.gov/pubmed/19889224 http://dx.doi.org/10.1186/1742-2094-6-32 |
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