Inherent promoter bidirectionality facilitates maintenance of sequence integrity and transcription of parasitic DNA in mammalian genomes

BACKGROUND: Many mammalian genes are arranged in a bidirectional manner, sharing a common promoter and regulatory elements. This is especially true for promoters containing a CpG island, usually unmethylated and associated with an 'open' or accessible chromatin structure. In evolutionary t...

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Detalles Bibliográficos
Autores principales: Kalitsis, Paul, Saffery, Richard
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777200/
https://www.ncbi.nlm.nih.gov/pubmed/19860919
http://dx.doi.org/10.1186/1471-2164-10-498

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777200/
https://www.ncbi.nlm.nih.gov/pubmed/19860919
http://dx.doi.org/10.1186/1471-2164-10-498

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