The Specificity of the FOXL2 c.402C>G Somatic Mutation: A Survey of Solid Tumors

BACKGROUND: A somatic mutation in the FOXL2 gene is reported to be present in almost all (97%; 86/89) morphologically defined, adult-type, granulosa-cell tumors (A-GCTs). This FOXL2 c.402C>G mutation changes a highly conserved cysteine residue to a tryptophan (p.C134W). It was also found in a min...

Descripción completa

Detalles Bibliográficos
Autores principales: Schrader, Kasmintan A., Gorbatcheva, Bella, Senz, Janine, Heravi-Moussavi, Alireza, Melnyk, Nataliya, Salamanca, Clara, Maines-Bandiera, Sarah, Cooke, Susanna L., Leung, Peter, Brenton, James D., Gilks, C. Blake, Monahan, John, Huntsman, David G.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777318/
https://www.ncbi.nlm.nih.gov/pubmed/19956657
http://dx.doi.org/10.1371/journal.pone.0007988

Ejemplares similares

Ejemplares similares