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Structures of KaiC Circadian Clock Mutant Proteins: A New Phosphorylation Site at T426 and Mechanisms of Kinase, ATPase and Phosphatase

BACKGROUND: The circadian clock of the cyanobacterium Synechococcus elongatus can be reconstituted in vitro by three proteins, KaiA, KaiB and KaiC. Homo-hexameric KaiC displays kinase, phosphatase and ATPase activities; KaiA enhances KaiC phosphorylation and KaiB antagonizes KaiA. Phosphorylation an...

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Detalles Bibliográficos
Autores principales: Pattanayek, Rekha, Mori, Tetsuya, Xu, Yao, Pattanayek, Sabuj, Johnson, Carl H., Egli, Martin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777353/
https://www.ncbi.nlm.nih.gov/pubmed/19956664
http://dx.doi.org/10.1371/journal.pone.0007529