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Inferring Binding Energies from Selected Binding Sites
We employ a biophysical model that accounts for the non-linear relationship between binding energy and the statistics of selected binding sites. The model includes the chemical potential of the transcription factor, non-specific binding affinity of the protein for DNA, as well as sequence-specific p...
Autores principales: | Zhao, Yue, Granas, David, Stormo, Gary D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777355/ https://www.ncbi.nlm.nih.gov/pubmed/19997485 http://dx.doi.org/10.1371/journal.pcbi.1000590 |
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