Dosage Regulation of the Active X Chromosome in Human Triploid Cells

In mammals, dosage compensation is achieved by doubling expression of X-linked genes in both sexes, together with X inactivation in females. Up-regulation of the active X chromosome may be controlled by DNA sequence–based and/or epigenetic mechanisms that double the X output potentially in response...

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Detalles Bibliográficos
Autores principales: Deng, Xinxian, Nguyen, Di Kim, Hansen, R. Scott, Van Dyke, Daniel L., Gartler, Stanley M., Disteche, Christine M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777382/
https://www.ncbi.nlm.nih.gov/pubmed/19997486
http://dx.doi.org/10.1371/journal.pgen.1000751

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