Cargando…

G Protein Subunit Dissociation and Translocation Regulate Cellular Response to Receptor Stimulation

We examined the role of G proteins in modulating the response of living cells to receptor activation. The response of an effector, phospholipase C-β to M3 muscarinic receptor activation was measured using sensors that detect the generation of inositol triphosphate or diacylglycerol. The recently dis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chisari, Mariangela, Saini, Deepak Kumar, Cho, Joon-Ho, Kalyanaraman, Vani, Gautam, N.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777387/ https://www.ncbi.nlm.nih.gov/pubmed/19936219 http://dx.doi.org/10.1371/journal.pone.0007797

Ejemplares similares

Subcellular optogenetic activation of Cdc42 controls local and distal signaling to drive immune cell migration
por: O’Neill, Patrick R., et al.
Publicado: (2016)

Autoinactivation of the Stargazin–AMPA Receptor Complex: Subunit-Dependency and Independence from Physical Dissociation
por: Semenov, Artur, et al.
Publicado: (2012)

PKA regulation of neuronal function requires the dissociation of catalytic subunits from regulatory subunits
por: Xiong, Wei-Hong, et al.
Publicado: (2023)

Mutation in the M1 Domain of the Acetylcholine Receptor α Subunit Decreases the Rate of Agonist Dissociation
por: Wang, Hai-Long, et al.
Publicado: (1997)

Dissociations within short-term memory in GluA1 AMPA receptor subunit knockout mice
por: Taylor, Amy M., et al.
Publicado: (2011)

Expulsion mechanism of the substrate-translocating subunit in ECF transporters
por: Thangaratnarajah, Chancievan, et al.
Publicado: (2023)

Ligand induced dissociation of the AR homodimer precedes AR monomer translocation to the nucleus
por: Shizu, Ryota, et al.
Publicado: (2019)

Cellular Diversity and Differential Subcellular Localization of the G-Protein G(αo) Subunit in the Mouse Cerebellum
por: Roldán-Sastre, Alberto, et al.
Publicado: (2021)

Listerin-Dependent Nascent Protein Ubiquitination Relies on Ribosome Subunit Dissociation
por: Shao, Sichen, et al.
Publicado: (2013)

Subunit pI Can Influence Protein Complex Dissociation Characteristics
por: Leney, Aneika C.
Publicado: (2019)

Model of ribosomal translocation coupled with intra- and inter-subunit rotations
por: Xie, Ping
Publicado: (2015)

Perturbation of ribosomal subunit dynamics by inhibitors of tRNA translocation
por: Belardinelli, Riccardo, et al.
Publicado: (2021)

Translocation of subunit PPSE in plipastatin synthase and synthesis of novel lipopeptides
por: Gao, Ling, et al.
Publicado: (2022)

Dissociating Sensory and Motor Components of Inhibition of Return
por: Sereno, Anne B., et al.
Publicado: (2006)

Double Dissociation of Spike Timing–Dependent Potentiation and Depression by Subunit-Preferring NMDA Receptor Antagonists in Mouse Barrel Cortex
por: Banerjee, Abhishek, et al.
Publicado: (2009)

Dissociating Representations of Time and Number in Reinforcement-Rate Learning by Deletion of the GluA1 AMPA Receptor Subunit in Mice
por: Austen, Joseph M., et al.
Publicado: (2021)

Muscarinic receptors stimulate AC2 by novel phosphorylation sites, whereas Gβγ subunits exert opposing effects depending on the G-protein source
por: Shen, Jia X., et al.
Publicado: (2012)

ISOLATION OF CYTOPLASMIC AND CHLOROPLAST RIBOSOMES AND THEIR DISSOCIATION INTO ACTIVE SUBUNITS FROM CHLAMYDOMONAS REINHARDTII
por: Chua, Nam-Hai, et al.
Publicado: (1973)

Ubiquitin and TFIIH-stimulated DDB2 dissociation drives DNA damage handover in nucleotide excision repair
por: Ribeiro-Silva, Cristina, et al.
Publicado: (2020)

G protein gamma subunit, a hidden master regulator of GPCR signaling
por: Kankanamge, Dinesh, et al.
Publicado: (2022)

Receptor Tyrosine Kinase ErbB2 Translocates into Mitochondria and Regulates Cellular Metabolism
por: Ding, Yan, et al.
Publicado: (2012)

Isolated beta-heavy chain subunit of dynein translocates microtubules in vitro
Publicado: (1988)

The Ca(2+) channel β subunit determines whether stimulation of G(q)-coupled receptors enhances or inhibits N current
por: Heneghan, John F., et al.
Publicado: (2009)

Molecular and Cellular Mechanisms of Apoptosis during Dissociated Spermatogenesis
por: Liu, Tengfei, et al.
Publicado: (2017)

Eukaryotic G protein-coupled receptors as descendants of prokaryotic sodium-translocating rhodopsins
por: Shalaeva, Daria N., et al.
Publicado: (2015)

Glial metabotropic glutamate receptor-4 increases maturation and survival of oligodendrocytes
por: Spampinato, Simona Federica, et al.
Publicado: (2015)

Succinate and its G-protein-coupled receptor stimulates osteoclastogenesis
por: Guo, Yuqi, et al.
Publicado: (2017)

I-18 Chronic muscle electrical stimulation in Myotonic Dystrophy
por: Chisari, C.
Publicado: (2011)

Agonist-induced dimer dissociation as a macromolecular step in G protein-coupled receptor signaling
por: Petersen, Julian, et al.
Publicado: (2017)

Adaptation of the Mitochondrial Genome in Cephalopods: Enhancing Proton Translocation Channels and the Subunit Interactions
por: Almeida, Daniela, et al.
Publicado: (2015)

The Ion-Translocating NrfD-Like Subunit of Energy-Transducing Membrane Complexes
por: Calisto, Filipa, et al.
Publicado: (2021)

G-protein coupling and nuclear translocation of the human abscisic acid receptor LANCL2
por: Fresia, Chiara, et al.
Publicado: (2016)

Cellular Activity of Salmonella Typhimurium ArtAB Toxin and Its Receptor-Binding Subunit
por: Overgaard, Elise, et al.
Publicado: (2021)

Protein translocation across the ER requires a functional GTP binding site in the alpha subunit of the signal recognition particle receptor
Publicado: (1992)

The signal sequence receptor has a second subunit and is part of a translocation complex in the endoplasmic reticulum as probed by bifunctional reagents
Publicado: (1990)

Research Advances in Heterotrimeric G-Protein α Subunits and Uncanonical G-Protein Coupled Receptors in Plants
por: Liu, Ying, et al.
Publicado: (2021)

The ER Protein Translocation Channel Subunit Sbh1 Controls Virulence of Cryptococcus neoformans
por: Santiago-Tirado, Felipe H., et al.
Publicado: (2023)

The depletion of F(1) subunit ε in yeast leads to an uncoupled respiratory phenotype that is rescued by mutations in the proton-translocating subunits of F(0)
por: Tetaud, Emmanuel, et al.
Publicado: (2014)

Insulin regulates Rab3–Noc2 complex dissociation to promote GLUT4 translocation in rat adipocytes
por: Koumanov, Francoise, et al.
Publicado: (2015)

Inhibiting PTEN Protects Hippocampal Neurons against Stretch Injury by Decreasing Membrane Translocation of AMPA Receptor GluR2 Subunit
por: Liu, Yuan, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_he6slrkmq71vnd2staqfhp1u4l