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Generation and Characterization of Mice Carrying a Conditional Allele of the Wwox Tumor Suppressor Gene

WWOX, the gene that spans the second most common human chromosomal fragile site, FRA16D, is inactivated in multiple human cancers and behaves as a suppressor of tumor growth. Since we are interested in understanding WWOX function in both normal and cancer tissues we generated mice harboring a condit...

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Detalles Bibliográficos
Autores principales:	Ludes-Meyers, John H., Kil, Hyunsuk, Parker-Thornburg, Jan, Kusewitt, Donna F., Bedford, Mark T., Aldaz, C. Marcelo
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777388/ https://www.ncbi.nlm.nih.gov/pubmed/19936220 http://dx.doi.org/10.1371/journal.pone.0007775

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