Alternative-splicing-based bicistronic vectors for ratio-controlled protein expression and application to recombinant antibody production

In the last decade polycistronic vectors have become essential tools for both basic science and gene therapy applications. In order to co-express heterologous polypeptides, different systems have been developed from Internal Ribosome Entry Site (IRES) based vectors to the use of the 2A peptide. Unfo...

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Detalles Bibliográficos
Autores principales: Fallot, Stéphanie, Ben Naya, Raouia, Hieblot, Corinne, Mondon, Philippe, Lacazette, Eric, Bouayadi, Khalil, Kharrat, Abdelhakim, Touriol, Christian, Prats, Hervé
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777421/
https://www.ncbi.nlm.nih.gov/pubmed/19729510
http://dx.doi.org/10.1093/nar/gkp716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777421/
https://www.ncbi.nlm.nih.gov/pubmed/19729510
http://dx.doi.org/10.1093/nar/gkp716

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