Cargando…
Alternative-splicing-based bicistronic vectors for ratio-controlled protein expression and application to recombinant antibody production
In the last decade polycistronic vectors have become essential tools for both basic science and gene therapy applications. In order to co-express heterologous polypeptides, different systems have been developed from Internal Ribosome Entry Site (IRES) based vectors to the use of the 2A peptide. Unfo...
| Autores principales: | , , , , , , , , |
|---|---|
| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2009
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777421/ https://www.ncbi.nlm.nih.gov/pubmed/19729510 http://dx.doi.org/10.1093/nar/gkp716 |