FIGfams: yet another set of protein families

We present FIGfams, a new collection of over 100 000 protein families that are the product of manual curation and close strain comparison. Using the Subsystem approach the manual curation is carried out, ensuring a previously unattained degree of throughput and consistency. FIGfams are based on over...

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Detalles Bibliográficos
Autores principales: Meyer, Folker, Overbeek, Ross, Rodriguez, Alex
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Computational Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777423/
https://www.ncbi.nlm.nih.gov/pubmed/19762480
http://dx.doi.org/10.1093/nar/gkp698
Descripción
Sumario:We present FIGfams, a new collection of over 100 000 protein families that are the product of manual curation and close strain comparison. Using the Subsystem approach the manual curation is carried out, ensuring a previously unattained degree of throughput and consistency. FIGfams are based on over 950 000 manually annotated proteins and across many hundred Bacteria and Archaea. Associated with each FIGfam is a two-tiered, rapid, accurate decision procedure to determine family membership for new proteins. FIGfams are freely available under an open source license. These can be downloaded at ftp://ftp.theseed.org/FIGfams/. The web site for FIGfams is http://www.theseed.org/wiki/FIGfams/

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