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Biophysical characterizations of human mitochondrial transcription factor A and its binding to tumor suppressor p53

Human mitochondrial transcription factor A (TFAM) is a multi-functional protein, involved in different aspects of maintaining mitochondrial genome integrity. In this report, we characterized TFAM and its interaction with tumor suppressor p53 using various biophysical methods. DNA-free TFAM is a ther...

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Detalles Bibliográficos
Autores principales:	Wong, Tuck Seng, Rajagopalan, Sridharan, Freund, Stefan M., Rutherford, Trevor J., Andreeva, Antonina, Townsley, Fiona M., Petrovich, Miriana, Fersht, Alan R.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777442/ https://www.ncbi.nlm.nih.gov/pubmed/19755502 http://dx.doi.org/10.1093/nar/gkp750

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