Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption

The SRS2 (Suppressor of RAD Six screen mutant 2) gene encodes an ATP-dependent DNA helicase that regulates homologous recombination in Saccharomyces cerevisiae. Mutations in SRS2 result in a hyper-recombination phenotype, sensitivity to DNA damaging agents and synthetic lethality with mutations that...

Descripción completa

Detalles Bibliográficos
Autores principales: Colavito, Sierra, Macris-Kiss, Margaret, Seong, Changhyun, Gleeson, Olive, Greene, Eric C., Klein, Hannah L., Krejci, Lumir, Sung, Patrick
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777448/
https://www.ncbi.nlm.nih.gov/pubmed/19745052
http://dx.doi.org/10.1093/nar/gkp748

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777448/
https://www.ncbi.nlm.nih.gov/pubmed/19745052
http://dx.doi.org/10.1093/nar/gkp748

Ejemplares similares