Cargando…

Functional significance of the Rad51-Srs2 complex in Rad51 presynaptic filament disruption

The SRS2 (Suppressor of RAD Six screen mutant 2) gene encodes an ATP-dependent DNA helicase that regulates homologous recombination in Saccharomyces cerevisiae. Mutations in SRS2 result in a hyper-recombination phenotype, sensitivity to DNA damaging agents and synthetic lethality with mutations that...

Descripción completa

Detalles Bibliográficos
Autores principales:	Colavito, Sierra, Macris-Kiss, Margaret, Seong, Changhyun, Gleeson, Olive, Greene, Eric C., Klein, Hannah L., Krejci, Lumir, Sung, Patrick
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2009
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777448/ https://www.ncbi.nlm.nih.gov/pubmed/19745052 http://dx.doi.org/10.1093/nar/gkp748

Ejemplares similares

Protein dynamics of human RPA and RAD51 on ssDNA during assembly and disassembly of the RAD51 filament
por: Ma, Chu Jian, et al.
Publicado: (2017)

Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state
por: Špírek, Mário, et al.
Publicado: (2018)

Rad51 presynaptic filament stabilization function of the mouse Swi5–Sfr1 heterodimeric complex
por: Tsai, Shang-Pu, et al.
Publicado: (2012)

Enhancement of ADP release from the RAD51 presynaptic filament by the SWI5-SFR1 complex
por: Su, Guan-Chin, et al.
Publicado: (2014)

Contributions of the RAD51 N-terminal domain to BRCA2-RAD51 interaction
por: Subramanyam, Shyamal, et al.
Publicado: (2013)

The Shu complex interacts with Rad51 through the Rad51 paralogues Rad55–Rad57 to mediate error-free recombination
por: Godin, Stephen, et al.
Publicado: (2013)

The β-isoform of BCCIP promotes ADP release from the RAD51 presynaptic filament and enhances homologous DNA pairing
por: Kelso, Andrew A., et al.
Publicado: (2017)

RAD51 paralogs synergize with RAD51 to protect reversed forks from cellular nucleases
por: Guh, Chia-Lun, et al.
Publicado: (2023)

Rad54 and Rdh54 prevent Srs2-mediated disruption of Rad51 presynaptic filaments
por: Meir, Aviv, et al.
Publicado: (2022)

Microcephaly family protein MCPH1 stabilizes RAD51 filaments
por: Chang, Hao-Yen, et al.
Publicado: (2020)

FANCI-FANCD2 stabilizes the RAD51-DNA complex by binding RAD51 and protects the 5′-DNA end
por: Sato, Koichi, et al.
Publicado: (2016)

Human RAD51 paralogue RAD51C fosters repair of alkylated DNA by interacting with the ALKBH3 demethylase
por: Mohan, Monisha, et al.
Publicado: (2019)

Cooperation of RAD51 and RAD54 in regression of a model replication fork
por: Bugreev, Dmitry V., et al.
Publicado: (2011)

Differential requirement of Srs2 helicase and Rad51 displacement activities in replication of hairpin-forming CAG/CTG repeats
por: Nguyen, Jennifer H.G., et al.
Publicado: (2017)

Swi5-Sfr1 protein stimulates Rad51-mediated DNA strand exchange reaction through organization of DNA bases in the presynaptic filament
por: Fornander, Louise H., et al.
Publicado: (2014)

Inter-subunit interactions that coordinate Rad51's activities
por: Grigorescu, Arabela A., et al.
Publicado: (2009)

RAD54 family translocases counter genotoxic effects of RAD51 in human tumor cells
por: Mason, Jennifer M., et al.
Publicado: (2015)

Effect of the BRCA2 CTRD domain on RAD51 filaments analyzed by an ensemble of single molecule techniques
por: Holthausen, J. T., et al.
Publicado: (2011)

Rad51 gain-of-function mutants that exhibit high affinity DNA binding cause DNA damage sensitivity in the absence of Srs2
por: Malik, Punjab S., et al.
Publicado: (2008)

ATP-dependent nucleosome unwrapping catalyzed by human RAD51
por: North, Justin A., et al.
Publicado: (2013)

RI-1: a chemical inhibitor of RAD51 that disrupts homologous recombination in human cells
por: Budke, Brian, et al.
Publicado: (2012)

Tel1 and Rad51 are involved in the maintenance of telomeres with capping deficiency
por: Di Domenico, Enea Gino, et al.
Publicado: (2013)

Roles of Rad51 paralogs for promoting homologous recombination in Leishmania infantum
por: Genois, Marie-Michelle, et al.
Publicado: (2015)

RAD51 and RTEL1 compensate telomere loss in the absence of telomerase
por: Olivier, Margaux, et al.
Publicado: (2018)

RAD51 interconnects between DNA replication, DNA repair and immunity
por: Bhattacharya, Souparno, et al.
Publicado: (2017)

RADX condenses single-stranded DNA to antagonize RAD51 loading
por: Zhang, Hongshan, et al.
Publicado: (2020)

TOPORS-mediated RAD51 SUMOylation facilitates homologous recombination repair
por: Hariharasudhan, Gurusamy, et al.
Publicado: (2022)

Detection of novel recombinases in bacteriophage genomes unveils Rad52, Rad51 and Gp2.5 remote homologs
por: Lopes, Anne, et al.
Publicado: (2010)

Rad51 and Rad54 promote noncrossover recombination between centromere repeats on the same chromatid to prevent isochromosome formation
por: Onaka, Atsushi T., et al.
Publicado: (2016)

Caffeine inhibits gene conversion by displacing Rad51 from ssDNA
por: Tsabar, Michael, et al.
Publicado: (2015)

Role of the RAD51–SWI5–SFR1 Ensemble in homologous recombination
por: Su, Guan-Chin, et al.
Publicado: (2016)

Conformational flexibility and oligomerization of BRCA2 regions induced by RAD51 interaction
por: Sidhu, Arshdeep, et al.
Publicado: (2020)

Single-molecule localization microscopy reveals molecular transactions during RAD51 filament assembly at cellular DNA damage sites
por: Haas, Kalina T, et al.
Publicado: (2018)

Rad52-Rad51 association is essential to protect Rad51 filaments against Srs2, but facultative for filament formation
por: Ma, Emilie, et al.
Publicado: (2018)

Ca(2+) improves organization of single-stranded DNA bases in human Rad51 filament, explaining stimulatory effect on gene recombination
por: Fornander, Louise H., et al.
Publicado: (2012)

GEMIN2 promotes accumulation of RAD51 at double-strand breaks in homologous recombination
por: Takizawa, Yoshimasa, et al.
Publicado: (2010)

Interactions between BRCA2 and RAD51 for promoting homologous recombination in Leishmania infantum
por: Genois, Marie-Michelle, et al.
Publicado: (2012)

Involvement of ATM in homologous recombination after end resection and RAD51 nucleofilament formation
por: Bakr, A., et al.
Publicado: (2015)

RAD51B plays an essential role during somatic and meiotic recombination in Physcomitrella
por: Charlot, Florence, et al.
Publicado: (2014)

A cell-penetrating antibody inhibits human RAD51 via direct binding
por: Turchick, Audrey, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_urebjmcngv45c34mo07u7tksm4