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Protein kinase C promotes restoration of calcium homeostasis to platelet activating factor-stimulated human neutrophils by inhibition of phospholipase C
BACKGROUND: The role of protein kinase C (PKC) in regulating the activity of phospholipase C (PLC) in neutrophils activated with the chemoattractant, platelet-activating factor (PAF, 20 and 200 nM), was probed in the current study using the selective PKC inhibitors, GF10903X (0.5 - 1 μM) and stauros...
Autores principales: | Tintinger, Gregory R, Theron, Annette J, Steel, Helen C, Cockeran, Riana, Pretorius, Lynette, Anderson, Ronald |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777896/ https://www.ncbi.nlm.nih.gov/pubmed/19874629 http://dx.doi.org/10.1186/1476-9255-6-29 |
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