Antiretroviral activity of the aminothiol WR1065 against Human Immunodeficiency virus (HIV-1) in vitro and Simian Immunodeficiency virus (SIV) ex vivo

BACKGROUND: WR1065 is the free-thiol metabolite of the cytoprotective aminothiol amifostine, which is used clinically at very high doses to protect patients against toxicity induced by radiation and chemotherapy. In an earlier study we briefly reported that the aminothiol WR1065 also inhibits HIV-1...

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Detalles Bibliográficos
Autores principales: Poirier, Miriam C, Olivero, Ofelia A, Hardy, Andrew W, Franchini, Genoveffa, Borojerdi, Jennifer P, Walker, Vernon E, Walker, Dale M, Shearer, Gene M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2009
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777914/
https://www.ncbi.nlm.nih.gov/pubmed/19895691
http://dx.doi.org/10.1186/1742-6405-6-24

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777914/
https://www.ncbi.nlm.nih.gov/pubmed/19895691
http://dx.doi.org/10.1186/1742-6405-6-24

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