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Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting

BACKGROUND: Testicular germ cell tumors (TGCTs) are classified as seminonas or non-seminomas of which a major subset is embryonal carcinoma (EC) that can differentiate into diverse tissues. The pluripotent nature of human ECs resembles that of embryonic stem (ES) cells. Many Wnt signalling species a...

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Detalles Bibliográficos
Autores principales:	Snow, Grace E, Kasper, Allison C, Busch, Alexander M, Schwarz, Elisabeth, Ewings, Katherine E, Bee, Thomas, Spinella, Michael J, Dmitrovsky, Ethan, Freemantle, Sarah J
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2009
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2777936/ https://www.ncbi.nlm.nih.gov/pubmed/19874621 http://dx.doi.org/10.1186/1471-2407-9-383

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