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Direct Activation of RhoA by Reactive Oxygen Species Requires a Redox-Sensitive Motif
BACKGROUND: Rho family GTPases are critical regulators of the cytoskeleton and affect cell migration, cell-cell adhesion, and cell-matrix adhesion. As with all GTPases, their activity is determined by their guanine nucleotide-bound state. Understanding how Rho proteins are activated and inactivated...
| Autores principales: | , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2009
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778012/ https://www.ncbi.nlm.nih.gov/pubmed/19956681 http://dx.doi.org/10.1371/journal.pone.0008045 |