Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium

Erythrocyte measures are heritable and have important health implications, yet their genetic determinants are largely unknown. We performed genome-wide association analyses in 24,167 European-ancestry individuals for six erythrocyte traits and identified associations at 23 loci (P values 5×10(-8) to...

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Detalles Bibliográficos
Autores principales: Ganesh, Santhi K., Zakai, Neil A., van Rooij, Frank J A., Soranzo, Nicole, Smith, Albert V., Nalls, Michael A., Chen, Ming-Huei, Kottgen, Anna, Glazer, Nicole L., Dehghan, Abbas, Kuhnel, Brigitte, Aspelund, Thor, Yang, Qiong, Tanaka, Toshiko, Jaffe, Andrew, Bis, Joshua C M., Verwoert, Germaine C., Teumer, Alexander, Fox, Caroline S., Guralnik, Jack M., Ehret, Georg B., Rice, Kenneth, Felix, Janine F., Rendon, Augusto, Eiriksdottir, Gudny, Levy, Daniel, Patel, Kushang V., Boerwinkle, Eric, Rotter, Jerome I., Hofman, Albert, Sambrook, Jennifer G., Hernandez, Dena, Zheng, Gang, Bandinelli, Stefania, Singleton, Andrew B., Coresh, Josef, Lumley, Thomas, Uitterlinden, André G., vanGils, Janine M., Launer, Lenore J., Cupples, L. Adrienne, Oostra, Ben A., Zwaginga, Jaap-Jan, Ouwehand, Willem H., Thein, Swee-Lay, Meisinger, Christa, Deloukas, Panos, Nauck, Matthias, Spector, Tim, Gieger, Christian, Gudnason, Vilmundur, van Duijn, Cornelia M., Psaty, Bruce M., Ferrucci, Luigi, Chakravarti, Aravinda, Greinacher, Andreas, O’Donnell, Christopher J., Witteman, Jacqueline C M., Furth, Susan, Cushman, Mary, Harris, Tamara B., Lin, Jing-Ping
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778265/
https://www.ncbi.nlm.nih.gov/pubmed/19862010
http://dx.doi.org/10.1038/ng.466

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