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Processing and population genetic analysis of multigenic datasets with ProSeq3 software

Motivation: The current tendency in molecular population genetics is to use increasing numbers of genes in the analysis. Here I describe a program for handling and population genetic analysis of DNA polymorphism data collected from multiple genes. The program includes a sequence/alignment editor and...

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Detalles Bibliográficos
Autor principal: Filatov, Dmitry A.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778335/
https://www.ncbi.nlm.nih.gov/pubmed/19797407
http://dx.doi.org/10.1093/bioinformatics/btp572
Descripción
Sumario:Motivation: The current tendency in molecular population genetics is to use increasing numbers of genes in the analysis. Here I describe a program for handling and population genetic analysis of DNA polymorphism data collected from multiple genes. The program includes a sequence/alignment editor and an internal relational database that simplify the preparation and manipulation of multigenic DNA polymorphism datasets. The most commonly used DNA polymorphism analyses are implemented in ProSeq3, facilitating population genetic analysis of large multigenic datasets. Extensive input/output options make ProSeq3 a convenient hub for sequence data processing and analysis. Availability: The program is available free of charge from http://dps.plants.ox.ac.uk/sequencing/proseq.htm Contact: dmitry.filatov@plants.ox.ac.uk