Mechanisms of HTLV-1 persistence and transformation

Adult T-cell leukaemia (ATL) is caused by the human T-cell lymphotropic virus type 1 (HTLV-1). HTLV-1 has elaborated strategies to persist and replicate in the presence of a strong immune response. In this review, we summarise these mechanisms and their contribution to T-cell transformation and ATL...

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Detalles Bibliográficos
Autores principales: Boxus, M, Willems, L
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Minireview
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778510/
https://www.ncbi.nlm.nih.gov/pubmed/19861996
http://dx.doi.org/10.1038/sj.bjc.6605345
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author Boxus, M
Willems, L
author_facet Boxus, M
Willems, L
author_sort Boxus, M
collection PubMed
description Adult T-cell leukaemia (ATL) is caused by the human T-cell lymphotropic virus type 1 (HTLV-1). HTLV-1 has elaborated strategies to persist and replicate in the presence of a strong immune response. In this review, we summarise these mechanisms and their contribution to T-cell transformation and ATL development.
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spelling pubmed-27785102010-11-03 Mechanisms of HTLV-1 persistence and transformation Boxus, M Willems, L Br J Cancer Minireview Adult T-cell leukaemia (ATL) is caused by the human T-cell lymphotropic virus type 1 (HTLV-1). HTLV-1 has elaborated strategies to persist and replicate in the presence of a strong immune response. In this review, we summarise these mechanisms and their contribution to T-cell transformation and ATL development. Nature Publishing Group 2009-11-03 2009-09-29 /pmc/articles/PMC2778510/ /pubmed/19861996 http://dx.doi.org/10.1038/sj.bjc.6605345 Text en Copyright © 2009 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Minireview
Boxus, M
Willems, L
Mechanisms of HTLV-1 persistence and transformation
title Mechanisms of HTLV-1 persistence and transformation
title_full Mechanisms of HTLV-1 persistence and transformation
title_fullStr Mechanisms of HTLV-1 persistence and transformation
title_full_unstemmed Mechanisms of HTLV-1 persistence and transformation
title_short Mechanisms of HTLV-1 persistence and transformation
title_sort mechanisms of htlv-1 persistence and transformation
topic Minireview
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778510/
https://www.ncbi.nlm.nih.gov/pubmed/19861996
http://dx.doi.org/10.1038/sj.bjc.6605345
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