Tumour-targeted delivery of TRAIL using Salmonella typhimurium enhances breast cancer survival in mice

BACKGROUND: An effective cancer therapeutic must selectively target tumours with minimal systemic toxicity. Expression of a cytotoxic protein using Salmonella typhimurium would enable spatial and temporal control of delivery because these bacteria preferentially target tumours over normal tissue. ME...

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Detalles Bibliográficos
Autores principales: Ganai, S, Arenas, R B, Forbes, N S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Translational Therapeutics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778534/
https://www.ncbi.nlm.nih.gov/pubmed/19861961
http://dx.doi.org/10.1038/sj.bjc.6605403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778534/
https://www.ncbi.nlm.nih.gov/pubmed/19861961
http://dx.doi.org/10.1038/sj.bjc.6605403

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