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Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers
Ivabradine, an I (f) inhibitor, acts primarily on the sinoatrial node and is used to reduce the heart rate with minimal effect on myocardial contractility, blood pressure, and intracardiac conduction. Heart rate reduction is an important aspect of care in patients with chronic stable angina and hear...
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Formato: | Texto |
Lenguaje: | English |
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SAGE-Hindawi Access to Research
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778565/ https://www.ncbi.nlm.nih.gov/pubmed/19936114 http://dx.doi.org/10.4061/2009/179350 |
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author | Liang, Michael Puri, Aniket Devlin, Gerard |
author_facet | Liang, Michael Puri, Aniket Devlin, Gerard |
author_sort | Liang, Michael |
collection | PubMed |
description | Ivabradine, an I (f) inhibitor, acts primarily on the sinoatrial node and is used to reduce the heart rate with minimal effect on myocardial contractility, blood pressure, and intracardiac conduction. Heart rate reduction is an important aspect of care in patients with chronic stable angina and heart failure. Many patients with coronary artery disease have coexisting asthma or chronic obstructive airway disease, and most of them are unable to tolerate beta blockers. Ivabradine may thus be a useful medicine in therapeutic heart rate management especially in patients who are intolerant of beta-blockers. |
format | Text |
id | pubmed-2778565 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | SAGE-Hindawi Access to Research |
record_format | MEDLINE/PubMed |
spelling | pubmed-27785652009-11-23 Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers Liang, Michael Puri, Aniket Devlin, Gerard Cardiol Res Pract Review Article Ivabradine, an I (f) inhibitor, acts primarily on the sinoatrial node and is used to reduce the heart rate with minimal effect on myocardial contractility, blood pressure, and intracardiac conduction. Heart rate reduction is an important aspect of care in patients with chronic stable angina and heart failure. Many patients with coronary artery disease have coexisting asthma or chronic obstructive airway disease, and most of them are unable to tolerate beta blockers. Ivabradine may thus be a useful medicine in therapeutic heart rate management especially in patients who are intolerant of beta-blockers. SAGE-Hindawi Access to Research 2009 2009-07-30 /pmc/articles/PMC2778565/ /pubmed/19936114 http://dx.doi.org/10.4061/2009/179350 Text en Copyright © 2009 Michael Liang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Liang, Michael Puri, Aniket Devlin, Gerard Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers |
title | Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers |
title_full | Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers |
title_fullStr | Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers |
title_full_unstemmed | Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers |
title_short | Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers |
title_sort | heart rate and cardiovascular disease: an alternative to beta blockers |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778565/ https://www.ncbi.nlm.nih.gov/pubmed/19936114 http://dx.doi.org/10.4061/2009/179350 |
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