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Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers

Ivabradine, an I (f) inhibitor, acts primarily on the sinoatrial node and is used to reduce the heart rate with minimal effect on myocardial contractility, blood pressure, and intracardiac conduction. Heart rate reduction is an important aspect of care in patients with chronic stable angina and hear...

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Detalles Bibliográficos
Autores principales: Liang, Michael, Puri, Aniket, Devlin, Gerard
Formato: Texto
Lenguaje:English
Publicado: SAGE-Hindawi Access to Research 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778565/
https://www.ncbi.nlm.nih.gov/pubmed/19936114
http://dx.doi.org/10.4061/2009/179350
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author Liang, Michael
Puri, Aniket
Devlin, Gerard
author_facet Liang, Michael
Puri, Aniket
Devlin, Gerard
author_sort Liang, Michael
collection PubMed
description Ivabradine, an I (f) inhibitor, acts primarily on the sinoatrial node and is used to reduce the heart rate with minimal effect on myocardial contractility, blood pressure, and intracardiac conduction. Heart rate reduction is an important aspect of care in patients with chronic stable angina and heart failure. Many patients with coronary artery disease have coexisting asthma or chronic obstructive airway disease, and most of them are unable to tolerate beta blockers. Ivabradine may thus be a useful medicine in therapeutic heart rate management especially in patients who are intolerant of beta-blockers.
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spelling pubmed-27785652009-11-23 Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers Liang, Michael Puri, Aniket Devlin, Gerard Cardiol Res Pract Review Article Ivabradine, an I (f) inhibitor, acts primarily on the sinoatrial node and is used to reduce the heart rate with minimal effect on myocardial contractility, blood pressure, and intracardiac conduction. Heart rate reduction is an important aspect of care in patients with chronic stable angina and heart failure. Many patients with coronary artery disease have coexisting asthma or chronic obstructive airway disease, and most of them are unable to tolerate beta blockers. Ivabradine may thus be a useful medicine in therapeutic heart rate management especially in patients who are intolerant of beta-blockers. SAGE-Hindawi Access to Research 2009 2009-07-30 /pmc/articles/PMC2778565/ /pubmed/19936114 http://dx.doi.org/10.4061/2009/179350 Text en Copyright © 2009 Michael Liang et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Liang, Michael
Puri, Aniket
Devlin, Gerard
Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers
title Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers
title_full Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers
title_fullStr Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers
title_full_unstemmed Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers
title_short Heart Rate and Cardiovascular Disease: An Alternative to Beta Blockers
title_sort heart rate and cardiovascular disease: an alternative to beta blockers
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2778565/
https://www.ncbi.nlm.nih.gov/pubmed/19936114
http://dx.doi.org/10.4061/2009/179350
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